3D Cell Culture
Product types
Consumables
Cell Culture
Always committed to innovation, Corning provides an extensive range of 3D cell culture solutions, emphasizing their role in advancing research in areas such as drug discovery, cancer biology, tissue engineering, and regenerative medicine.
Advantages of 3D Cell Culture
- 3D models mimic in vivo-like environments better than 2D cultures, offering more biologically relevant results for drug discovery, disease modelling, and tissue engineering.
- Benefits include improved accuracy in drug testing, higher success rates, reduced costs, and faster paths to market.
Overview of models
- Spheroid Models
- Simple, multicellular 3D structures formed via cell aggregation.
- Scaffold-free methods include suspension cultures, attachment-resistant surfaces like Corning Ultra-Low Attachment (ULA) surfaces.
- Applications: cancer research, stem cell biology, and drug screening.
- Organoids:
- Mini-organs derived from stem cells or organ progenitors, mimicking organ-specific cell types and functions.
- Used for personalized medicine, disease modelling, and drug discovery.
- Supported by hydrogels.
- Hydrogels and ECM Scaffold Models:
- Natural hydrogels (e.g., Matrigel matrix, Collagen) and synthetic hydrogels (e.g., Synthegel) provide 3D growth environments for cell culture.
- Applications include organoid formation, cancer research, and stem cell differentiation.
- Solid Synthetic Scaffold Models:
- Porous structures made from synthetic materials.
- Used for organotypic tissue models, air-liquid interface cultures, bioprinting, and motility studies.
